1.Definition

Endogenous field thermotherapy uses two sets of current of different frequencies to cross vertically in the deep part of the human body, and the interfering electric field is generated at the crossing, which heats up the temperature of tumor tissues to 42.5℃～43.5℃ and lasts for more than 40 minutes, causing the growth of tumor cells to be blocked and killed. It not only has direct cytotoxic effect on tumor cells, but also enhances the efficacy of chemotherapy and radiotherapy, improves the body's immunity and inhibits tumor metastasis.

2.Mechanism

Tumor tissue has twisted and dilated blood vessels, high resistance to blood flow, incomplete vascular receptor , poor sensitivity to temperature, difficulty in heat dissipation under high temperature, easy focusing of heat, and there is a temperature difference of 5-10℃ with the normal tissues; whereas the normal cells can tolerate the high temperature of 42.5℃～43.5℃ for a long time. Thermotherapy kills tumor cells by heating while normal cells are not affected, and does not cause adverse reactions such as bone marrow suppression and hair loss.

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3. Why high heat can kill tumor cells?

(1)High heat will damage the membrane of cancer cells, meanwhile, high heat will inhibit the synthesis of DNA and RNA and protein, so that the proliferation of cancer cells will be inhibited, leading to cell death.
(2)High heat increases lysosomal activity in cancer cells and releases acid hydrolase in large quantities, leading to rupture of cytomembrane, cytoplasmic spillage and death of cancer cells.
(3)High heat inhibits the respiration of cancer cells, leading to the increase of anaerobic glycolysis and the accumulation of lactic acid, and the increase of acidity promotes the increase of enzyme activity, which ultimately leads to cell death.
(4) High heat protects, activates and improves the immune function of human body and improves the body's ability to remove cancer cells, which is incomparable with traditional radiotherapy and even surgery.

4. Advantages

• *No significant side effects
• *Temperature control by computer system
• *Direct heating of body surface and deep tumor sites
• *Combined application with radiotherapy and chemotherapy to further improve the efficacy of radiotherapy and chemotherapy

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5.Clinical application

• *Body surface tumor
• *Malignant hydrothorax and ascites
• *Deep tumors of chest, abdomen and pelvis
• *Esophageal cancer, lung cancer, stomach cancer, intestinal cancer, liver cancer, ovarian cancer, uterine cancer, etc.